Increasing Public Awareness and Provider Education About Primary Immunodeficiency Disease
Primary Immunodeficiency Diseases (PID) are a group of primarily single-gene disorders of the immune system.
Primary denotes the genetic nature of the defects, differentiating them from secondary or acquired immunodeficiencies caused by malnutrition, infection, chemotherapy, or other external agents.
The defining characteristics of primary immunodeficiency diseases make them candidates for a public health intervention approach.
Although the clinical manifestations and underlying genetic defects are diverse, primary immunodeficiency diseases share the common feature of increased susceptibility to infection and collectively result in substantial morbidity and shortened life spans.
However prompt diagnosis and treatment can be lifesaving and may result in marked improvements in the quality and length of life.
The heterogeneity of primary immunodeficiency diseases and the limited understanding of the relation between genotype and phenotype also hinder intervention efforts.
Additional obstacles include the difficulty of diagnosis in the absence of a high index of suspicion and the lack of awareness of health care providers and the public which impedes the timely recognition of affected person by using a combination of clinical suspicion and diagnostic testing.
Primary denotes the genetic nature of the defects, differentiating them from secondary or acquired immunodeficiencies caused by malnutrition, infection, chemotherapy, or other external agents.
The defining characteristics of primary immunodeficiency diseases make them candidates for a public health intervention approach.
Although the clinical manifestations and underlying genetic defects are diverse, primary immunodeficiency diseases share the common feature of increased susceptibility to infection and collectively result in substantial morbidity and shortened life spans.
However prompt diagnosis and treatment can be lifesaving and may result in marked improvements in the quality and length of life.
The heterogeneity of primary immunodeficiency diseases and the limited understanding of the relation between genotype and phenotype also hinder intervention efforts.
Additional obstacles include the difficulty of diagnosis in the absence of a high index of suspicion and the lack of awareness of health care providers and the public which impedes the timely recognition of affected person by using a combination of clinical suspicion and diagnostic testing.
Related Programs
Centers for Research and Demonstration for Health Promotion and Disease Prevention
Department of Health and Human Services
Agency: Department of Health and Human Services
Office: Centers for Disease Control - OD
Estimated Funding: $15,000,000
Office: Centers for Disease Control - OD
Estimated Funding: $15,000,000
Who's Eligible
Obtain Full Opportunity Text:
https://grants.nih.gov/grants/guide/pa-files/PAR-23-042.html
Additional Information of Eligibility:
Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U. S. Territory or Possession.
Full Opportunity Web Address:
http://grants.nih.gov/grants/guide/pa-files/PAR-23-042.html
Contact:
Agency Email Description:
msb4@cdc.gov
Agency Email:
Date Posted:
2023-04-07
Application Due Date:
Archive Date:
2023-06-22
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