Research Grants to Develop and Validate a Prognostic Tool of Mental Health Sequelae After Traumatic Brain Injury for Adolescent Patients (U01)
The Centers for Disease Control and Prevention's National Center for Injury Prevention and Control (NCIPC) is soliciting investigator-initiated research proposals to conduct a well-designed, longitudinal study within a large pediatric healthcare system(s) serving a diverse patient population, to
derive and validate a new prognostic tool that identifies adolescents (ages 11-17 years) at increased risk for mental health sequelae or a worsening of an existing mental health condition(s).
Of particular interest is research that focuses on adolescent populations shown to have higher rates of traumatic brain injury (TBI) incidence or greater risk of negative post-TBI outcomes (e.g., Black and Hispanic youth, youth living in rural areas, and those without insurance).
The primary objectives of this NOFO are:
Identification of risk/protective factors in the acute care setting that can predict new or worsening mental health sequelae within the three (3) months following a TBI among adolescents (ages 11-17 years Development of a new prognostic tool, based on empirically derived risk/protective factors, that can aid in predicting which adolescents in a clinical setting are more likely to subsequently develop mental health sequelae or experience a worsening of an existing mental health condition(s).
Validation of the new empirically derived tool’s ability to accurately predict the development of mental health sequelae or experience a worsening of an existing mental health condition(s).
Secondary Outcomes:
Secondary outcomes for this project include publications and presentations describing results; new/modified recommendations for pediatric mTBI guideline(s); recommendations related to improving the feasibility of implementing the tool within a healthcare system; development and promotion of communication products related to the prognostic tool; potential development of a module/application based on the prognostic tool that is compatible and interoperable with multiple EHR vendors.
Of particular interest is research that focuses on adolescent populations shown to have higher rates of traumatic brain injury (TBI) incidence or greater risk of negative post-TBI outcomes (e.g., Black and Hispanic youth, youth living in rural areas, and those without insurance).
The primary objectives of this NOFO are:
Identification of risk/protective factors in the acute care setting that can predict new or worsening mental health sequelae within the three (3) months following a TBI among adolescents (ages 11-17 years Development of a new prognostic tool, based on empirically derived risk/protective factors, that can aid in predicting which adolescents in a clinical setting are more likely to subsequently develop mental health sequelae or experience a worsening of an existing mental health condition(s).
Validation of the new empirically derived tool’s ability to accurately predict the development of mental health sequelae or experience a worsening of an existing mental health condition(s).
Secondary Outcomes:
Secondary outcomes for this project include publications and presentations describing results; new/modified recommendations for pediatric mTBI guideline(s); recommendations related to improving the feasibility of implementing the tool within a healthcare system; development and promotion of communication products related to the prognostic tool; potential development of a module/application based on the prognostic tool that is compatible and interoperable with multiple EHR vendors.
Related Programs
Injury Prevention and Control Research and State and Community Based Programs
Department of Health and Human Services
Agency: Department of Health and Human Services
Office: Centers for Disease Control and Prevention - ERA
Estimated Funding: $5,500,000
Office: Centers for Disease Control and Prevention - ERA
Estimated Funding: $5,500,000
Who's Eligible
Relevant Nonprofit Program Categories
Obtain Full Opportunity Text:
Veterans Business Outreach Center - Expansion FY23
Additional Information of Eligibility:
See Section III.
Eligibility Information
Full Opportunity Web Address:
https://www.grantsolutions.gov/gs/preaward/previewPublicAnnouncement.do?id=101287
Contact:
Agency Email Description:
MPanero@cdc.gov
Agency Email:
Date Posted:
2022-11-16
Application Due Date:
Archive Date:
2023-02-23
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